Statin Trials

It probably started when medical authorities put the blame for heart disease (atherosclerosis) on circulating cholesterol. In the modern era, this goes back to the 1950s or before, when heart disease was still relatively rare, but increasing. Heart disease became publicly prominent in 1955, when US President Eisenhower suffered a heart attack (which he survived).

Read More…

Does cholesterol cause heart disease?

Briefly, the cholesterol hypothesis proposes that by getting into arterial walls and causing atherosclerosis (plaque buildup in arteries), cholesterol increases the risk of cardiovascular disease (CVD) and cerebrovascular disease (strokes). However, according to a perhaps unlikely source – the American Heart Association: “Exactly how atherosclerosis starts or what causes it isn’t known.” That’s an admission

Read More…

The marketing science of Lipitor

Statins have become the most profitable class of drugs in the history of medicine, and the most profitable of them all has been Lipitor (Atorvastatin), manufactured by Pfizer (the largest pharmaceutical company by revenue). Here is a Lipitor advertisement from the early 2000’s highlighting that, in patients with multiple risk factors for heart disease, Lipitor

Read More…