The statin class of drugs are widely prescribed to reduce blood cholesterol levels, according to the hypothesis that this will reduce the risk of heart disease and benefit the individual taking the statin. However, like most drugs, it is inevitable that statins will have unanticipated effects in certain individuals. While some of these effects might
It probably started when medical authorities put the blame for heart disease (atherosclerosis) on circulating cholesterol. In the modern era, this goes back to the 1950s or before, when heart disease was still relatively rare, but increasing. Heart disease became publicly prominent in 1955, when US President Eisenhower suffered a heart attack (which he survived).
Statins have become the most profitable class of drugs in the history of medicine, and the most profitable of them all has been Lipitor (Atorvastatin), manufactured by Pfizer (the largest pharmaceutical company by revenue). Here is a Lipitor advertisement from the early 2000’s highlighting that, in patients with multiple risk factors for heart disease, Lipitor